“Never give up,” the Dalai Lama says. This is the memoir of a man whose circumstances — and spirit — required him to live by this principle his whole life. Beginning in pain and poverty, Howard Sachs’ life story has been a quest to ease the suffering of as many people as he could, in as many third world countries as he could reach, and experience as much of nature’s glory as he could discover. He speaks of the highs and lows on his journey with frankness and wit, and often has a sharp point to make, such as how criminal it is of governments to neglect their people’s need for access to health care. Though he was frustrated by the lack of infrastructure, he never gave up.